Bcl-2 Family

Catalog No.Inhibitor Name Bcl-2Bcl-BBcl-wBcl-xLMcl-1A1BaxOther
A10255ABT-737
****
*
***
***
A10022Navitoclax (ABT-263)
****
****
****
**
**
A10665Obatoclax Mesylate
***
A10955TW-37
***
*
***
A12500Venetoclax
****
***
****
A15004AT101
**
**
***
A11448HA14-1
*
A12823Sabutoclax
**
**
***
**
A15545A-1210477
****
A14222UMI-77
**
A11988Gambogic Acid
*
*
****
*
*
*
Caspase
A12743BM-1074
****
****
A13327WEHI-539 hydrochloride
****
A15821BDA-366
***
A16061BH3I-1
*
p53
A16112A-1155463
****
A16190A-1331852
****
A16314Apogossypolone (ApoG2)

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Bax-activator-106

    Catalog No. A18406
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    Bax agonist
    Bax-activator-106 is a specific Bax agonist. It acts by promoting Bax-dependent but not Bak-dependent apoptosis. 了解更多
  2. Muristerone A

    Catalog No. A15340
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    EcR 激动剂
    Muristerone A是蜕皮激素的植物蜕皮激素类固醇类似物,可在哺乳动物细胞中诱导基因并在野生型Bax转染的细胞中引起细胞凋亡。 了解更多

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