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Belinostat (PXD101)

目录号: A10122
HDAC 抑制剂
Belinostat (PXD101) 是一种 HDAC 抑制剂,在 HeLa 细胞提取物中抑制 HDAC 活性,其 IC50 为 27 nM。
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规格 价格 库存 数量
10mg
¥210.00
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25mg
¥350.00
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50mg
¥560.00
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100mg
¥875.00
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200mg
¥1,400.00
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10mM * 1mL in DMSO
¥245.00
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Belinostat (PXD101)发表的1篇文献
  • Shariful Islam, .et al. , Blood Adv, 2020, 4(20): 5297-5310 PMID: 33108458
  • 生物活性
    Discription Belinostat (PXD101) is a HDAC inhibitor that inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM.
    Targets
    Target Value
    产品信息
    目录号 A10122
    分子式 C15H14N2O4S
    分子量 318.4
    CAS号 414864-00-9
    SMILES C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
    其他名称 PX105684
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 56 mg/mL (175.9 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 31.41 mL 157.04 mL 314.07 mL
    0.5 mM 6.28 mL 31.41 mL 62.81 mL
    1 mM 3.14 mL 15.7 mL 31.41 mL
    5 mM 0.63 mL 3.14 mL 6.28 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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