Belizatinib

Name: Belizatinib
SKU: A20919
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A20919

ALK/TRKA/TRKB/TRKC 抑制剂

Belizatinib 是一种口服的、双重的、强效的 ALK 和 TRKA、TRKB、TRKC 抑制剂，对野生型重组 ALK 激酶的 IC50 为 0.7 nM。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥560.00	现货
10mg	¥945.00	现货
25mg	¥1,960.00	现货
50mg	¥2,730.00	现货
100mg	¥3,850.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Belizatinib is an oral, dual, potent inhibitor of ALK and TRKA, TRKB, and TRKC, with IC50 of 0.7?nM for wild-type recombinant ALK kinase.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20919
分子式	C33H44FN5O3
分子量	577.73
CAS号	1357920-84-3
SMILES	O=C(NC1=NC2=CC=C(CN3CCC(C(C)(O)C)CC3)C=C2N1[C@H]4CC[C@@H](C(NC(C)C)=O)CC4)C5=CC=C(F)C=C5
其他名称	TSR 011, TSR011
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	96 mg/mL (166.17 mM)
	Water	Insoluble
	Ethanol	96 mg/mL (166.17 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.31 mL	86.55 mL	173.09 mL
0.5 mM	3.46 mL	17.31 mL	34.62 mL
1 mM	1.73 mL	8.65 mL	17.31 mL
5 mM	0.35 mL	1.73 mL	3.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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