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Benzthiazide is a long-acting diuretic and a hypertension agent. Benzthiazide is an inhibitor of carbonic anhydrase 9 (CA9), with Kis of 8.0, 8.8 and 10 nM for CA9, CA2 and CA1, respectively. Benzthiazide also suppresses proliferation of cancer cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.15 mL | 115.76 mL | 231.51 mL |
| 0.5 mM | 4.63 mL | 23.15 mL | 46.3 mL |
| 1 mM | 2.32 mL | 11.58 mL | 23.15 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.63 mL |
*The above data is based on the productmolecular weight 431.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17355 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 431.94 |
| Formula | C15H14ClN3O4S3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 91-33-8 |
| Synonyms | Benzthiazide; Benzothiazide; Dihydrex; Aquatag; Diucen; Exna; Edemax; Foven; Dytide |
| SMILES | O=S(N=C1CSCC2=CC=CC=C2)(C3=CC(S(=O)(N)=O)=C(Cl)C=C3N1)=O |
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