Bergaptol
目录号: A12303
CYP3A4 enzyme 抑制剂
Bergaptol 是一种羟基化的补骨脂素，它作为 CYP3A4 酶的去苄基化活性的强效抑制剂，具有 IC50 值为 24.92 uM。最近的研究表明，它可能具有抗增殖和抗癌特性。
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生物活性
| Discription | Bergaptol is a hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 uM. Recent studies suggest that it may have antiproliferative and anticancer properties. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12303 |
|---|---|
| 分子式 | C11H6O4 |
| 分子量 | 202.16 |
| CAS号 | 486-60-2 |
| SMILES | O=C1C=CC(C(O1)=C2)=C(O)C3=C2OC=C3 |
| 其他名称 | 5-Hydroxypsoralen; 4-Hydroxybergapten |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 38 mg/mL (187.97 mM) | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 49.47 mL | 247.33 mL | 494.66 mL |
| 0.5 mM | 9.89 mL | 49.47 mL | 98.93 mL |
| 1 mM | 4.95 mL | 24.73 mL | 49.47 mL |
| 5 mM | 0.99 mL | 4.95 mL | 9.89 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 486-60-2 | 486-60-2 供应商 | 486-60-2 花费 | 486-60-2 生产商 | 订购 486-60-2 | 486-60-2 代理商