Betaxolol
目录号: A11721
Betaxolol 是一种选择性 beta1 受体阻滞剂，用于治疗高血压和青光眼。由于其对 beta1 受体 的选择性，与非选择性 beta-阻滞剂相比，它通常具有较少的系统性副作用，例如不会引起由 beta2 受体 调节的支气管痉挛（如 Timolol 可能引起的）。Betaxolol 也显示出比 Metoprolol 更高的对 beta1 受体 的亲和力。
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生物活性
| Discription | Betaxolol is a selective beta1 receptor blocker used in the treatment of hypertension and glaucoma. Being selective for beta1 receptors, it typically has fewer systemic side effects than non-selective beta-blockers, for example, not causing bronchospasm (mediated by beta2 receptors) as timolol may. Betaxolol also shows greater affininty for beta1 receptors than metoprolol. |
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产品信息
| 目录号 | A11721 |
|---|---|
| 分子式 | C18H29NO3 |
| 分子量 | 307.43 |
| CAS号 | 63659-18-7 |
| SMILES | CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O |
| 其他名称 | Betoptic |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 57 mg/mL (185.41 mM) | |
| Water | 57 mg/mL (185.41 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.53 mL | 162.64 mL | 325.28 mL |
| 0.5 mM | 6.51 mL | 32.53 mL | 65.06 mL |
| 1 mM | 3.25 mL | 16.26 mL | 32.53 mL |
| 5 mM | 0.65 mL | 3.25 mL | 6.51 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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