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Betrixaban是一种抗凝血药，可作为直接Xa因子抑制剂。它具有强大的，口服活性和对因子Xa的高度选择性，由于其低hERG亲和力而从一组相似的化合物中选择。
| In vitro | DMSO | 32 mg/mL (70.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.13 mL | 110.64 mL | 221.28 mL |
| 0.5 mM | 4.43 mL | 22.13 mL | 44.26 mL |
| 1 mM | 2.21 mL | 11.06 mL | 22.13 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
*The above data is based on the productmolecular weight 451.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12518 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 451.91 |
| Formula | C23H22ClN5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 330942-05-7 |
| Synonyms | PRT-054,021, PRT-054021 |
| SMILES | CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl |
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