Betrixaban
目录号: A12518
FXa 抑制剂
Betrixaban 是一种抗凝药物，其作用机制为直接抑制因子 Xa。它具有强效、口服活性，并且对因子 Xa 具有高度选择性，从一组类似化合物中被选出，因其对 hERG 的亲和力低。
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生物活性
| Discription | Betrixaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is potent, orally active and highly selective for factor Xa, being selected from a group of similar compounds for its low hERG affinity. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12518 |
|---|---|
| 分子式 | C23H22ClN5O3 |
| 分子量 | 451.91 |
| CAS号 | 330942-05-7 |
| SMILES | CN(C)C(=N)C1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)OC)C(=O)NC3=NC=C(C=C3)Cl |
| 其他名称 | PRT-054,021, PRT-054021 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 32 mg/mL (70.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.13 mL | 110.64 mL | 221.28 mL |
| 0.5 mM | 4.43 mL | 22.13 mL | 44.26 mL |
| 1 mM | 2.21 mL | 11.06 mL | 22.13 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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