Bexmarilimab (FP-1305) is a humanized IgG4 monoclonal antibody that targets CLEVER-1 with a high affinity, demonstrated by an IC50 value of 4.51 nM. This antibody is effective in inducing a phenotypic switch from M2 to M1 in tumor-associated macrophages, a process critical for modulating the immune environment in oncological research. Bexmarilimab is primarily utilized in the study of cancer immunotherapy and tumor microenvironment dynamics.
Bexmarilimab (FP-1305) is a humanized IgG4 monoclonal antibody that targets CLEVER-1 with a high affinity, demonstrated by an IC50 value of 4.51 nM. This antibody is effective in inducing a phenotypic switch from M2 to M1 in tumor-associated macrophages, a process critical for modulating the immune environment in oncological research. Bexmarilimab is primarily utilized in the study of cancer immunotherapy and tumor microenvironment dynamics.
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