BFH772
目录号: A16342
VEGFR2 抑制剂
BFH772 是一种强效的口服 VEGFR2 抑制剂，在针对 VEGFR2 激酶 方面具有高效性，其 IC50 值为 3 nM。
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生物活性
| Discription | BFH772 is a potent oral VEGFR2 inhibitor, which is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. | |||||
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产品信息
| 目录号 | A16342 |
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| 分子式 | C23H16F3N3O3 |
| 分子量 | 439.39 |
| CAS号 | 890128-81-1 |
| SMILES | O=C(C1=C2C=CC(OC3=NC=NC(CO)=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4 |
| 其他名称 | BFH-772, BFH 772 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 76 mg/mL (172.97 mM) | |
| Water | Insoluble | ||
| Ethanol | 76 mg/mL (172.97 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.76 mL | 113.79 mL | 227.59 mL |
| 0.5 mM | 4.55 mL | 22.76 mL | 45.52 mL |
| 1 mM | 2.28 mL | 11.38 mL | 22.76 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.55 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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