BG45

目录号: A11361

HDAC inhibitor

BG45

BG45 Chemical Structure

CAS NO. 926259-99-6

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 700.00
50 mg
¥ 2,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively).
Targets
HDAC3 HDAC1 HDAC2 HDAC6
289 nM2 μM2.2 μM>20 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 46.68 mL 233.4 mL 466.81 mL
0.5 mM 9.34 mL 46.68 mL 93.36 mL
1 mM 4.67 mL 23.34 mL 46.68 mL
5 mM 0.93 mL 4.67 mL 9.34 mL

*The above data is based on the productmolecular weight 214.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11361
MECHANISM OF ACTION Inhibitor
M. Wt 214.22
Formula C11H10N4O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 926259-99-6
Synonyms BG 45, BG-45
SMILES NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2

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