BI-1347
目录号: A18769
CDK8 抑制剂
BI-1347 是一种选择性的 CDK8/cyclin C 抑制剂，其 IC50 为 1.1 nM。
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生物活性
| Discription | BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM. | |||||
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| Targets |
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| Cell Research |
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产品信息
| 目录号 | A18769 |
|---|---|
| 分子式 | C22H20N4O |
| 分子量 | 356.43 |
| CAS号 | 2163056-91-3 |
| SMILES | O=C(N(C)C)CN1N=CC(C2=CC=C(C3=CN=CC4=C3C=CC=C4)C=C2)=C1 |
| 其他名称 | BI-1347; BI1347; BI 1347 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 70 mg/mL (196.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (8.41 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.06 mL | 140.28 mL | 280.56 mL |
| 0.5 mM | 5.61 mL | 28.06 mL | 56.11 mL |
| 1 mM | 2.81 mL | 14.03 mL | 28.06 mL |
| 5 mM | 0.56 mL | 2.81 mL | 5.61 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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