BI-1808 is a human IgG1 monoclonal antibody designed to selectively target TNFR2 (Tumor Necrosis Factor Receptor 2). It functions by inhibiting the interaction between TNFR2 and its ligand TNF-??. This antibody facilitates the Fc??R-dependent depletion of regulatory T cells (Tregs) and promotes the expansion of CD8+ T cells within the tumor microenvironment. BI-1808 is utilized in research focused on modulating immune responses and studying the mechanisms of immune evasion in cancer.
BI-1808 is a human IgG1 monoclonal antibody designed to selectively target TNFR2 (Tumor Necrosis Factor Receptor 2). It functions by inhibiting the interaction between TNFR2 and its ligand TNF-??. This antibody facilitates the Fc??R-dependent depletion of regulatory T cells (Tregs) and promotes the expansion of CD8+ T cells within the tumor microenvironment. BI-1808 is utilized in research focused on modulating immune responses and studying the mechanisms of immune evasion in cancer.
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