BI 2536

Name: BI 2536
SKU: A10134
Price: 210 CNY
Rating: 5 (11 reviews)

目录号: A10134

PLK 抑制剂

11 篇发表文献

BI 2536 是一种选择性的 Plk1 抑制剂，能在低纳摩尔浓度下抑制 Plk1 酶的活性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥455.00	现货
10mg	¥700.00	现货
25mg	¥840.00	现货
50mg	¥1,400.00	现货
100mg	¥2,520.00	现货
500mg	¥6,160.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用BI 2536发表的11篇文献

Ryuzaburo Yuki, .et al. , Eur J Pharmacol, 2024, Jan 15:963:176229 PMID: 38072041

Nuria Gallisa-Sune, .et al. , Nat Commun, 2023, Apr 27;14(1):2434 PMID: 37105961

Kei K Ito, .et al. , J Cell Biol, 2021, Mar 1;220(3):e202005153 PMID: 33492359

Ryuzaburo Yuki, .et al. , J Cell Mol Med, 2021, Feb;25(3):1677-1687 PMID: 33465289

Yamagishi A, .et al. , Int J Mol Sci, 2020, Feb 5;21(3) PMID: 32033461

Bucko PJ, .et al. , Elife, 2019, Dec 24;8. pii: e52220 PMID: 31872801

Watanabe K, .et al. , Nat Commun, 2019, Feb 25;10(1):931 PMID: 30804344

Valérian Pasche, .et al. , Parasit Vectors, 2018, 11: 298 PMID: 29764454

Takeshi Wakida, .et al. , eLife, 2017, 6: e29953 PMID: 29254517

Majid Momeny, .et al. , Sci Rep, 2017, 7: 4204 PMID: 28646172

Ifuji A, .et al. , Exp Cell Res, 2017, Nov 15;360(2):347-357 PMID: 28942021

生物活性

Discription

BI 2536 is a selective inhibitor of Plk1, which inhibits Plk1 enzyme activity at low nanomolar concentrations.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10134
分子式	C28H39N7O3
分子量	521.7
CAS号	755038-02-9
SMILES	CC[C@@H]1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	21 mg/mL (40.25 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (187.86 mM)
In vivo	30% PEG 400+0.5% Tween 80+5% Propylene glycol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.17 mL	95.84 mL	191.68 mL
0.5 mM	3.83 mL	19.17 mL	38.34 mL
1 mM	1.92 mL	9.58 mL	19.17 mL
5 mM	0.38 mL	1.92 mL	3.83 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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