BI-4464

目录号: A18894

PTK2/FAK inhibitor

BI-4464

BI-4464 Chemical Structure

CAS NO. 1227948-02-8

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.

库存: 现货

规格 价格 数量
1 mg
¥ 1,500.00
5 mg
¥ 4,200.00
10 mg
¥ 7,000.00
50 mg
¥ 21,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
In vitro DMSO 23 mg/mL (41.4 mM)
Water Insoluble
Ethanol 12 mg/mL (21.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18 mL 90 mL 180 mL
0.5 mM 3.6 mL 18 mL 36 mL
1 mM 1.8 mL 9 mL 18 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 555.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18894
作用机制 Inhibitor (抑制剂)
M. Wt 555.55
Formula C28H28F3N5O4
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1227948-02-8
Synonyms BI 4464, BI4464
SMILES O=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CC5)=C4C5=O)=N3)C(OC)=C2

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