BI-78D3

目录号: A13683

JNK inhibitor

BI-78D3

BI-78D3 Chemical Structure

CAS NO. 883065-90-5

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

库存: 现货

规格 价格 数量
10 mg
¥ 1,200.00
25 mg
¥ 2,500.00
50 mg
¥ 4,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).
Targets
JNK
280 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.39 mL 131.93 mL 263.85 mL
0.5 mM 5.28 mL 26.39 mL 52.77 mL
1 mM 2.64 mL 13.19 mL 26.39 mL
5 mM 0.53 mL 2.64 mL 5.28 mL

*The above data is based on the productmolecular weight 379. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13683
MECHANISM OF ACTION Inhibitor
M. Wt 379
Formula C13H9N5O5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 883065-90-5
Synonyms BI 78D3, BI78D3
SMILES C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]

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