BI-78D3

Name: BI-78D3
SKU: A13683
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A13683

JNK 抑制剂

BI-78D3 是一种竞争性的 JNK（c-Jun N-terminal kinases）抑制剂（IC50 = 280 nM），对 p38α 的选择性超过 100 倍，并且在 mTOR 和 PI-3K 上没有活性。BI 78D3 抑制 JIP1（JNK 互动蛋白 1）与 JNK 的结合（IC50 = 500 nM）。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥560.00	现货
25mg	¥1,155.00	现货
50mg	¥1,890.00	现货
100mg	¥3,010.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

BI-78D3 is a competitive JNK (c-Jun N-terminal kinases) inhibitor (IC50 = 280 nM) that displays > 100 fold selectivity over p38α and no activity at mTOR and PI-3K. BI 78D3 inhibits JIP1(JNK interacting protein 1)-JNK binding (IC50 = 500 nM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13683
分子式	C13H9N5O5S2
分子量	379
CAS号	883065-90-5
SMILES	C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
其他名称	BI 78D3, BI78D3
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (234.6 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.39 mL	131.93 mL	263.85 mL
0.5 mM	5.28 mL	26.39 mL	52.77 mL
1 mM	2.64 mL	13.19 mL	26.39 mL
5 mM	0.53 mL	2.64 mL	5.28 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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