BI-882370
目录号: A19734
RAF 抑制剂
BI-882370 是一种强效且选择性的 RAF激酶抑制剂,它与位于 BRAF激酶 DFG-out(非活性)构象中的激酶 ATP结合位点 结合。
| Discription | BI-882370 is a potent and selective RAF kinase inhibitor that binds to the ATP binding site of the kinase positioned in the DFG-out (inactive) conformation of the BRAF kinase. | |||||
|---|---|---|---|---|---|---|
| Targets |
|
|||||
| Cell Research |
|
| 目录号 | A19734 |
|---|---|
| 分子式 | C28H33F2N7O2S |
| 分子量 | 569.67 |
| CAS号 | 1392429-79-6 |
| SMILES | CCCS(=O)(NC1=CC=C(F)C(N2C=C(C3=CN=CN=C3)C4=NC(N(C5CCN(CC)CC5)C)=CC=C42)=C1F)=O |
| 其他名称 | BI882370, BI 882370 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2