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Bicalutamide (Casodex)是一种口服非甾体抗雄激素，用于治疗前列腺癌和多毛症。
靶点信息
| Androgen Receptor (LNCaP/AR(cs) cells) | ||||
| 0.16 μM |
| In vitro | DMSO | 84 mg/mL (195.17 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (11.61 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.23 mL | 116.17 mL | 232.34 mL |
| 0.5 mM | 4.65 mL | 23.23 mL | 46.47 mL |
| 1 mM | 2.32 mL | 11.62 mL | 23.23 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.65 mL |
*The above data is based on the productmolecular weight 430.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10142 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 430.4 |
| Formula | C18H14F4N2O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 90357-06-5 |
| Synonyms | Cosudex, Calutide, Kalumid |
| SMILES | CC(CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O |
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