Bictegravir

Name: Bictegravir
SKU: A17011
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A17011

HIV-1 integrase 抑制剂

1 篇发表文献

Bictegravir，也被称为 GS-9883，是一种强效的、无需增效剂的、每日一次的 HIV-1整合酶链转移抑制剂（INSTI）（IC50 - 1.6 nM），具有改进的药代动力学和体外耐药性特征。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,330.00	现货
50mg	¥2,205.00	现货
100mg	¥3,395.00	现货
500mg	¥7,805.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Bictegravir发表的1篇文献

Michal S Barski, .et al. , Nat Commun, 2021, Aug 17;12(1):4996 PMID: 34404793

生物活性

Discription	Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile.

产品信息

目录号	A17011
分子式	C21H18F3N3O5
分子量	449.38
CAS号	1611493-60-7
SMILES	O=C(C1=CN(C2=C(O)C1=O)C[C@@]3([H])O[C@](C4)([H])CC[C@]4([H])N3C2=O)NCC5=C(F)C=C(F)C=C5F
其他名称	GS-9883, GS 9883, GS9883
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	86 mg/mL (191.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.25 mL	111.26 mL	222.53 mL
0.5 mM	4.45 mL	22.25 mL	44.51 mL
1 mM	2.23 mL	11.13 mL	22.25 mL
5 mM	0.45 mL	2.23 mL	4.45 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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