bio-THZ1

目录号: A18559

covalent CDK7 inhibitor

bio-THZ1

bio-THZ1 Chemical Structure

CAS NO. 1604811-14-4

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 9.49 mL 47.45 mL 94.91 mL
0.5 mM 1.9 mL 9.49 mL 18.98 mL
1 mM 0.95 mL 4.75 mL 9.49 mL
5 mM 0.19 mL 0.95 mL 1.9 mL

*The above data is based on the productmolecular weight 1053.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A18559
作用机制 Inhibitor (抑制剂)
M. Wt 1053.67
Formula C52H65ClN12O8S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1604811-14-4
SMILES O=C(NCCOCCOCCOCCNC(NCCCN(C)C/C=C/C(NC1=CC=C(C(NC2=CC=CC(NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)=C2)=O)C=C1)=O)=O)CCCC[C@@H]6SC[C@]([C@]6([H])N7)([H])NC7=O

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