BIO

目录号: A17129

GSK3 抑制剂

BIO

BIO Chemical Structure

CAS NO. 667463-62-9

BIO是一种细胞可渗透的双吲哚(靛玉红)化合物,可作为GSK3α/β的强效,选择性,可逆和ATP竞争性抑制剂。IC50值为5 nM。

库存: 现货

规格 价格 数量
5 mg
¥ 850.00
10 mg
¥ 1,300.00
50 mg
¥ 4,900.00
100 mg
¥ 13,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BIO是一种细胞可渗透的双吲哚(靛玉红)化合物,可作为GSK3α/β的强效,选择性,可逆和ATP竞争性抑制剂。IC50值为5 nM。
In vitro (25°C) DMSO 70 mg/mL (196.53 mM)
Water Insoluble
Ethanol 6 mg/mL (16.84 mM)
In vivo 5% DMSO+40% PEG 300+5% Tween 80+50%ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.08 mL 140.38 mL 280.76 mL
0.5 mM 5.62 mL 28.08 mL 56.15 mL
1 mM 2.81 mL 14.04 mL 28.08 mL
5 mM 0.56 mL 2.81 mL 5.62 mL

*The above data is based on the productmolecular weight 356.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A17129
作用机制 Inhibitor (抑制剂)
M. Wt 356.18
Formula C16H10BrN3O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 667463-62-9
Synonyms GSK3 Inhibitor IX, MLS 2052, MLS-2052, MLS2052
SMILES O=C(/C1=C2NC3=C(C\2=N/O)C=CC=C3)NC4=C1C=CC(Br)=C4

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