6-Biopterin
目录号: A13901
NOS cofactor
Biopterin 是四氢-L-生物蝶呤（BH4）的氧化形式，它是一种一氧化氮合酶（NOS）辅因子。L-生物蝶呤可以通过硫氧还蛋白还原酶，随后是二氢蝶呤还原酶或还原型谷胱甘肽还原为 BH4。它对培养中的人类黑色素细胞极为毒性（48小时后 IC50 = 0.2 uM）。
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生物活性
| Discription | Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 uM after 48 hrs). | ||
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产品信息
| 目录号 | A13901 |
|---|---|
| 分子式 | C9H11N5O3 |
| 分子量 | 237.2 |
| CAS号 | 22150-76-1 |
| SMILES | CC(C(C1=CN=C2C(=N1)C(=O)N=C(N2)N)O)O |
| 其他名称 | L-erythro-Biopterin, L-Biopterin, NSC 339699 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 1 mg/mL (4.21 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 42.16 mL | 210.79 mL | 421.59 mL |
| 0.5 mM | 8.43 mL | 42.16 mL | 84.32 mL |
| 1 mM | 4.22 mL | 21.08 mL | 42.16 mL |
| 5 mM | 0.84 mL | 4.22 mL | 8.43 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 22150-76-1 | 22150-76-1 供应商 | 22150-76-1 花费 | 22150-76-1 生产商 | 订购 22150-76-1 | 22150-76-1 代理商