Birinapant (TL32711)

Name: Birinapant (TL32711)
SKU: A12738
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A12738

XIAP/cIAP1 拮抗剂

1 篇发表文献

Birinapant，也被称为 TL32711，是一种合成的小分子和肽类模拟物，模仿线粒体来源的凋亡激活因子（SMAC）并抑制IAP（凋亡抑制蛋白）家族蛋白，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥770.00	现货
25mg	¥1,295.00	现货
50mg	¥1,890.00	现货
100mg	¥3,430.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Birinapant (TL32711)发表的1篇文献

Antonella Antignani, .et al. , FASEB J, 2023, Dec;37(12):e23292 PMID: 37971407

生物活性

Discription

Birinapant, also known as TL32711, is a synthetic small molecule and peptido mimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins, with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12738
分子式	C42H56F2N8O6
分子量	806.94
CAS号	1260251-31-7
SMILES	CC[C@@H](C(=O)N1C[C@H](C[C@H]1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)C[C@@H]6C[C@@H](CN6C(=O)[C@H](CC)NC(=O)[C@H](C)NC)O)O)NC(=O)[C@H](C)NC
其他名称	TL-32711, TL 32711
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	87 mg/mL (107.81 mM)
	Water	Insoluble
	Ethanol	48 mg/mL (59.48 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.39 mL	61.96 mL	123.92 mL
0.5 mM	2.48 mL	12.39 mL	24.78 mL
1 mM	1.24 mL	6.2 mL	12.39 mL
5 mM	0.25 mL	1.24 mL	2.48 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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