Bis(maltolato)oxovanadium(IV) is a reversible, competitive inhibitor targeting protein tyrosine phosphatases (PTPs). It demonstrates significant inhibitory activity against HCPTPA, PTP1B, HPTPβ, and SHP2, with IC50 values of 126 nM, 109 nM, 26 nM, and 201 nM, respectively. This compound serves as a powerful insulin sensitizer, making it a valuable tool for research in metabolic disorders and diabetes-related studies.
Bis(maltolato)oxovanadium(IV) is a reversible, competitive inhibitor targeting protein tyrosine phosphatases (PTPs). It demonstrates significant inhibitory activity against HCPTPA, PTP1B, HPTPβ, and SHP2, with IC50 values of 126 nM, 109 nM, 26 nM, and 201 nM, respectively. This compound serves as a powerful insulin sensitizer, making it a valuable tool for research in metabolic disorders and diabetes-related studies.
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