Bitopertin
目录号: A15021
Glycine reuptake 抑制剂
RG1678（Bitopertin）是一种强效的非竞争性甘氨酸再摄取抑制剂（GlyT1）。
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生物活性
| Discription | RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1). | ||
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产品信息
| 目录号 | A15021 |
|---|---|
| 分子式 | C21H20F7N3O4S |
| 分子量 | 543.46 |
| CAS号 | 845614-11-1 |
| SMILES | C[C@@H](C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F |
| 其他名称 | RG1678, RO4917838, RG-1678, RG 1678, RO-4917838, RO 4917838 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 89 mg/mL (163.76 mM) | |
| Water | Insoluble | ||
| Ethanol | 89 mg/mL (163.76 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.4 mL | 92 mL | 184.01 mL |
| 0.5 mM | 3.68 mL | 18.4 mL | 36.8 mL |
| 1 mM | 1.84 mL | 9.2 mL | 18.4 mL |
| 5 mM | 0.37 mL | 1.84 mL | 3.68 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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