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Bitopertin

Glycine reuptake 抑制剂

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产品目录号: A15021

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Bitopertin 5mg A15021-5
¥ 700.00
Bitopertin 10mg A15021-10
¥ 950.00
Bitopertin 50mg A15021-50
¥ 3,900.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).

Bitopertin

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Chemical Information

目录号 A15021
Mechanism of action Inhibitor
分子量 543.46
化学分子式 C21H20F7N3O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 845614-11-1
Synonyms RG1678, RO4917838, RG-1678, RG 1678, RO-4917838, RO 4917838
SMILES code CC(C(F)(F)F)OC1=C(C=C(C=C1)S(=O)(=O)C)C(=O)N2CCN(CC2)C3=C(C=C(C=N3)C(F)(F)F)F
化学名称 [4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[5-methylsulfonyl-2-[(2S)-1,1,1-trifluoropropan-2-yl]oxyphenyl]methanone

生物活性

Description
RG1678 (Bitopertin) is a potent and noncompetitive glycine reuptake inhibitor (GlyT1).
Targets
GlyT1
25nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 92 mL 184.01mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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