BIX02189

目录号: A21729

MEK5 inhibitor

BIX02189

BIX02189 Chemical Structure

CAS NO. 1265916-41-3

BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 810.00
10 mg
¥ 1,400.00
50 mg
¥ 4,140.00
100 mg
¥ 8,280.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BIX02189 is a potent and selective MEK5 inhibitor with an IC50 of 1.5 nM. BIX02189 also inhibits ERK5 catalytic activity with an IC50 of 59 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.7 mL 113.5 mL 226.99 mL
0.5 mM 4.54 mL 22.7 mL 45.4 mL
1 mM 2.27 mL 11.35 mL 22.7 mL
5 mM 0.45 mL 2.27 mL 4.54 mL

*The above data is based on the productmolecular weight 440.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21729
作用机制 Inhibitor (抑制剂)
M. Wt 440.54
Formula C27H28N4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1265916-41-3
Synonyms BIX 02189; BIX-02189
SMILES O=C(N(C)C)C1=CC(NC2=O)=C(/C2=C(C3=CC=CC=C3)/NC4=CC=CC(CN(C)C)=C4)C=C1.[(Z)]

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