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FGFR 抑制剂

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产品目录号: A15534


产品名 目录号 价格 数量
BLU9931 5mg A15534-5
¥ 1,100.00
BLU9931 10mg A15534-10
¥ 1,500.00
BLU9931 25mg A15534-25
¥ 2,200.00



BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),





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Chemical Information

目录号 A15534
Mechanism of action Inhibitor
分子量 509.38
化学分子式 C26H22Cl2N4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1538604-68-0
Synonyms BLU-9931, BLU 9931
SMILES code CC1=C(C(=CC=C1)NC(=O)C=C)NC2=NC=C3C=C(C=CC3=N2)C4=C(C(=CC(=C4Cl)OC)OC)Cl
化学名称 N-(2-(6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-ylamino)-3-methylphenyl)acrylamide


BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),
3 nM150 nM493 nM591 nM


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.63 mL 98.16 mL 196.32mL
0.5 mM 3.93 mL 19.63 mL 39.26 mL
1 mM 1.96 mL 9.82 mL 19.63 mL
5 mM 0.39 mL 1.96 mL 3.93 mL

*The above data is based on the productmolecular weight 509.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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