BLU9931

目录号: A15534

FGFR inhibitor

BLU9931 Chemical Structure

CAS NO. 1538604-68-0

BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 1,500.00
25 mg
¥ 2,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BLU9931 is the first selective small molecule inhibitor of FGFR4 with IC50 of 3 nM; less potent for FGFR1/2/3(IC50> 150 nM),
靶点信息
FGFR4 FGFR3 FGFR2 FGFR1
3 nM150 nM493 nM591 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.63 mL 98.16 mL 196.32 mL
0.5 mM 3.93 mL 19.63 mL 39.26 mL
1 mM 1.96 mL 9.82 mL 19.63 mL
5 mM 0.39 mL 1.96 mL 3.93 mL

*The above data is based on the productmolecular weight 509.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15534
MECHANISM OF ACTION Inhibitor
M. Wt 509.38
Formula C26H22Cl2N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1538604-68-0
Synonyms BLU-9931, BLU 9931
SMILES CC1=C(C(=CC=C1)NC(=O)C=C)NC2=NC=C3C=C(C=CC3=N2)C4=C(C(=CC(=C4Cl)OC)OC)Cl

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