BML-275 (Dorsomorphin)

目录号: A11970

AMPK inhibitor

BML-275 (Dorsomorphin) Chemical Structure

CAS NO. 866405-64-3

BML-275 is a cell-permeable pyrazolopyrimidine compound shown to be an AMP-activated protein kinase (AMPK) and fatty acid synthase inhibitor.

库存: 现货

规格 价格 数量
5 mg
¥ 500.00
10 mg
¥ 700.00
50 mg
¥ 2,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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BML-275 is a cell-permeable pyrazolopyrimidine compound shown to be an AMP-activated protein kinase (AMPK) and fatty acid synthase inhibitor.
Targets
AMPK
109 nM(Ki)
In vitro (25°C) DMSO 1 mg/mL warmed (2.5 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL warmed (5.0 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.03 mL 125.16 mL 250.31 mL
0.5 mM 5.01 mL 25.03 mL 50.06 mL
1 mM 2.5 mL 12.52 mL 25.03 mL
5 mM 0.5 mL 2.5 mL 5.01 mL

*The above data is based on the productmolecular weight 399.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11970
MECHANISM OF ACTION Inhibitor
M. Wt 399.5
Formula C24H25N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 866405-64-3
Synonyms BML275, BML 275
SMILES C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3

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