BMS-1166

Name: BMS-1166
SKU: A13129
Price: 420 CNY
Rating: 5 (288 reviews)

目录号: A13129

PD-1/PD-L1 interaction 抑制剂

BMS-1166 是一种强效的 PD-1/PD-L1 互作抑制剂，其 IC50 为 1.4 nM。BMS-1166 抵消了 PD-1/PD-L1 免疫检查点对 T 细胞激活的抑制作用。

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Grouped product items
规格	价格	库存
1mg	¥420.00	现货
5mg	¥1,050.00	现货
10mg	¥1,610.00	现货
25mg	¥3,115.00	现货
50mg	¥4,620.00	现货
100mg	¥6,895.00	现货
200mg	¥9,275.00	现货
*10mM 1mL in DMSO**	¥1,470.00	现货
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Data Sheet

SDS

Other Forms of BMS-1166

BMS-1166 hydrochloride

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生物活性

Discription

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13129
分子式	C36H33ClN2O7
分子量	641.11
CAS号	1818314-88-3
SMILES	O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1
其他名称	BMS 1166, BMS1166
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	91 mg/mL (141.93 mM)
	Water	Insoluble
	Ethanol	12 mg/mL (18.71 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.6 mL	77.99 mL	155.98 mL
0.5 mM	3.12 mL	15.6 mL	31.2 mL
1 mM	1.56 mL	7.8 mL	15.6 mL
5 mM	0.31 mL	1.56 mL	3.12 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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