BMS-265246

目录号: A11154

CDK inhibitor

BMS-265246

BMS-265246 Chemical Structure

CAS NO. 582315-72-8

BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D.

库存: 现货

规格 价格 数量
5 mg
¥ 1,800.00
10 mg
¥ 3,000.00
50 mg
¥ 8,000.00
100 mg
¥ 14,000.00
10mM * 1mL in DMSO
¥ 1,970.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D.
Targets
CDK1/CyclinB (Cell-free assay) CDK2/CyclinE (Cell-free assay) CDK4/CyclinD (Cell-free assay)
6 nM9 nM230 nM
In vitro (25°C) DMSO 20 mg/mL (57.91 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.96 mL 144.8 mL 289.6 mL
0.5 mM 5.79 mL 28.96 mL 57.92 mL
1 mM 2.9 mL 14.48 mL 28.96 mL
5 mM 0.58 mL 2.9 mL 5.79 mL

*The above data is based on the productmolecular weight 345.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11154
MECHANISM OF ACTION Inhibitor
M. Wt 345.3
Formula C18H17F2N3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 582315-72-8
Synonyms BMS265246
SMILES CCCCOC1=C2C=NNC2=NC=C1C(=O)C3=C(C=C(C=C3F)C)F

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