BMS-265246
目录号: A11154
CDK 抑制剂
BMS-265246 是一种新型的强效吡唑并[嘧啶]抑制剂，能够抑制 cdk2/cyclin E、cdk1/cyclin B 以及 cdk4/cyclin D。
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生物活性
| Discription | BMS-265246 is a potent new pyra- zolopyridine inhibitor of cdk2/cyclin E and cdk1/cyclin B, as well as cdk4/cyclin D. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11154 |
|---|---|
| 分子式 | C18H17F2N3O2 |
| 分子量 | 345.3 |
| CAS号 | 582315-72-8 |
| SMILES | CCCCOC1=C2C=NNC2=NC=C1C(=O)C3=C(C=C(C=C3F)C)F |
| 其他名称 | BMS265246 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 18 mg/mL (52.12 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.96 mL | 144.8 mL | 289.6 mL |
| 0.5 mM | 5.79 mL | 28.96 mL | 57.92 mL |
| 1 mM | 2.9 mL | 14.48 mL | 28.96 mL |
| 5 mM | 0.58 mL | 2.9 mL | 5.79 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 582315-72-8 | 582315-72-8 供应商 | 582315-72-8 花费 | 582315-72-8 生产商 | 订购 582315-72-8 | 582315-72-8 代理商