BMS 299897

目录号: A12444

γ-secretase 抑制剂

BMS 299897

BMS 299897 Chemical Structure

CAS NO. 290315-45-6

BMS 299897是一种有效的γ-分泌酶抑制剂(IC50 = 12 nM)。在体外抑制Aβ40和Aβ42的形成(IC50值分别为7.4和7.9 nM),并在体内降低脑,血浆和脑脊髓液中的Aβ。

库存: 现货

规格 价格 数量
10 mg
¥ 1,100.00
25 mg
¥ 2,200.00
50 mg
¥ 3,000.00
100 mg
¥ 6,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMS 299897是一种有效的γ-分泌酶抑制剂(IC50 = 12 nM)。在体外抑制Aβ40和Aβ42的形成(IC50值分别为7.4和7.9 nM),并在体内降低脑,血浆和脑脊髓液中的Aβ。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.53 mL 97.67 mL 195.34 mL
0.5 mM 3.91 mL 19.53 mL 39.07 mL
1 mM 1.95 mL 9.77 mL 19.53 mL
5 mM 0.39 mL 1.95 mL 3.91 mL

*The above data is based on the productmolecular weight 511.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12444
作用机制 Inhibitor (抑制剂)
M. Wt 511.94
Formula C24H21ClF3NO4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 290315-45-6
Synonyms BMS 299897
SMILES C[C@H](C1=C(C=C(C=C1)F)CCCC(=O)O)N(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

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