BMS 599626 HCl (AC480)

Name: BMS 599626 HCl (AC480)
SKU: A11209
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11209

EGFR 抑制剂

BMS 599626 是一种口服生物利用度的抑制剂，针对 HER1、HER2 和 HER4 酪氨酸激酶（分别为 IC50=22, 32 和 190 nM），具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥525.00	现货
10mg	¥875.00	现货
25mg	¥1,715.00	现货
50mg	¥2,765.00	现货
100mg	¥4,550.00	现货
*10mM 1mL in DMSO**	¥700.00	现货
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Data Sheet

SDS

Other Forms of BMS 599626 HCl (AC480)

BMS-599626

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生物活性

Discription	BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.

产品信息

目录号	A11209
分子式	C27H27FN8O3.HCl
分子量	567.1
CAS号	873837-23-1
SMILES	CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl
其他名称	BMS-599626, BMS599626, AC-480
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	104 mg/mL (196.02 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (33.92 mM)
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.63 mL	88.17 mL	176.34 mL
0.5 mM	3.53 mL	17.63 mL	35.27 mL
1 mM	1.76 mL	8.82 mL	17.63 mL
5 mM	0.35 mL	1.76 mL	3.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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