BMS 599626 (AC480)

目录号: A11209

EGFR Inhibitor

BMS 599626 (AC480)

BMS 599626 (AC480) Chemical Structure

CAS NO. 873837-23-1

BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
50 mg
¥ 4,000.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BMS 599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50=22, 32 and 190 nM, respectively) with potential antineoplastic activity.
In vitro (25°C) DMSO 113 mg/mL (199.29 mM)
Water <1 mg/mL (<1 mM)
Ethanol 20 mg/mL (35.27 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.63 mL 88.17 mL 176.34 mL
0.5 mM 3.53 mL 17.63 mL 35.27 mL
1 mM 1.76 mL 8.82 mL 17.63 mL
5 mM 0.35 mL 1.76 mL 3.53 mL

*The above data is based on the productmolecular weight 567.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11209
MECHANISM OF ACTION Inhibitor
M. Wt 567.1
Formula C27H27FN8O3.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 873837-23-1
Synonyms BMS-599626, BMS599626, AC-480
SMILES CC1=C2C(=NC=NN2C=C1NC(=O)OC[C@@H]3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F.Cl

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