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BMS-687453

促销

PPAR 激动剂

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产品目录号: A15836

库存状态:中国现货中国现货

产品名 目录号 价格 数量
BMS-687453 5mg A15836-5
¥ 1,100.00
BMS-687453 10mg A15836-10
¥ 1,800.00
BMS-687453 25mg A15836-25
¥ 3,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.

BMS-687453

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Chemical Information

目录号 A15836
Mechanism of action Agonist
分子量 444.86
化学分子式 C22H21ClN2O6
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1000998-59-3
Synonyms BMS687453, BMS 687453
SMILES code O=C(O)CN(CC1=CC=CC(OCC2=C(C)OC(C3=CC=C(Cl)C=C3)=N2)=C1)C(OC)=O
化学名称 N-(3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)-N-(methoxycarbonyl)glycine

生物活性

Description
BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.48 mL 112.39 mL 224.79mL
0.5 mM 4.5 mL 22.48 mL 44.96 mL
1 mM 2.25 mL 11.24 mL 22.48 mL
5 mM 0.45 mL 2.25 mL 4.5 mL

*The above data is based on the productmolecular weight 444.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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