BMT-145027

Name: BMT-145027
SKU: A12457

目录号: A12457

mGluR5 positive allosteric modulator

BMT-145027 Chemical Structure

CAS NO. 2018282-44-3

BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.

库存：现货

规格	价格	数量
1 mg	￥ 810.00
5 mg	￥ 2,430.00
10 mg	￥ 4,140.00
50 mg	￥ 12,420.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

BMT-145027 is an mGluR5 positive allosteric modulator without inherent agonist activity, exhibits an EC50 of 47 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.79 mL	113.94 mL	227.88 mL
0.5 mM	4.56 mL	22.79 mL	45.58 mL
1 mM	2.28 mL	11.39 mL	22.79 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12457
作用机制	Modulator (调节剂)
M. Wt	438.83
Formula	C23H14ClF3N4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2018282-44-3
Synonyms	BMT145027, BMT 145027
SMILES	ClC(C(C(F)(F)F)=C1)=CC=C1C2=NNC3=NC(C4=CC=CC=C4)=C(C#N)C(C5CC5)=C32