BMY 7378

目录号: A11208

5-HT1A agonist

BMY 7378 Chemical Structure

CAS NO. 21102-95-4

BMY 7378 is a 5-HT1A partial agonist and high affinity α1D adrenoceptor antagonist.

库存: 现货

规格 价格 数量
10 mg
¥ 400.00
50 mg
¥ 850.00
200 mg
¥ 3,200.00
10mM * 1mL in DMSO
¥ 770.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMY 7378 is a 5-HT1A partial agonist and high affinity α1D adrenoceptor antagonist.
Targets
Target Value
5-HT1ApIC50: 8.3
α1D-adrenoceptorpki: 8.2
DopamineD2receptorpIC50: 7.4
α2C-adrenoceptorpki: 6.54
5-HT1CpIC50: 6.4
5-HT1DpIC50: 5.9
H1receptorpIC50: 5.7
5-HT2pIC50: 5.5
H2receptorpIC50: 5.3
α2-adrenoceptor pIC50: 5.1
β1-adrenoceptor pIC50: 5.1
DopamineD1receptorpIC50: 5
NicotinicreceptorpIC50: 4.9
β2-adrenoceptor pIC50: <5.0
5-HT3pIC50: <5.0
H3receptorpIC50: <5.0
GABAAreceptorpIC50: <5.0
GABABreceptorpIC50: <5.0
MuscarinicM1receptorpIC50: <5.0
MuscarinicM2receptorpIC50: <5.0
MuscarinicM3receptorpIC50: <5.0
NMDAreceptorpIC50: <5.0
AT1receptorpIC50: <5.0
AT2receptorpIC50: <5.0
EndothelinReceptorpIC50: <5.0
AdenosineA1receptorpIC50: <5.0
AdenosineA2receptorpIC50: <5.0
In vitro (25°C) DMSO 92 mg/mL (200.68 mM)
Water 92 mg/mL (200.68 mM)
Ethanol 20 mg/mL (43.62 mM)
In vivo Saline 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.81 mL 109.07 mL 218.14 mL
0.5 mM 4.36 mL 21.81 mL 43.63 mL
1 mM 2.18 mL 10.91 mL 21.81 mL
5 mM 0.44 mL 2.18 mL 4.36 mL

*The above data is based on the productmolecular weight 458.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11208
MECHANISM OF ACTION Agonist
M. Wt 458.42
Formula C22H31N3O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 21102-95-4
Synonyms BMY7378, BMY-7378
SMILES COC1=CC=CC=C1N2CCN(CC2)CCN3C(=O)CC4(CCCC4)CC3=O.Cl.Cl

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