BNC101 is a human-specific monoclonal antibody that targets GPCR-LGR5, also known as GPR49. This antibody is designed for therapeutic use in the management of metastatic colorectal cancer (CRC), leveraging its specificity to bind to the LGR5 receptor, which plays a critical role in cancer stem cell biology and tumor growth. BNC101 holds potential for advancing CRC treatment by selectively targeting and modulating LGR5-expressing cells.
BNC101 is a human-specific monoclonal antibody that targets GPCR-LGR5, also known as GPR49. This antibody is designed for therapeutic use in the management of metastatic colorectal cancer (CRC), leveraging its specificity to bind to the LGR5 receptor, which plays a critical role in cancer stem cell biology and tumor growth. BNC101 holds potential for advancing CRC treatment by selectively targeting and modulating LGR5-expressing cells.
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