Bortezomib (Velcade)

Name: Bortezomib (Velcade)
SKU: A10160
Price: 175 CNY
Rating: 5 (17 reviews)

目录号: A10160

Proteasome 抑制剂

17 篇发表文献

Bortezomib 是一种高度选择性的、可逆的 26S 蛋白酶体 抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥455.00	现货
50mg	¥560.00	现货
100mg	¥980.00	现货
200mg	¥1,610.00	现货
500mg	¥2,695.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Bortezomib (Velcade)发表的17篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Yodita Asfaha, .et al. , Eur J Med Chem, 2024, 263: 115907

Tomoyuki Abe, .et al. , Eur J Pharmacol, 2022, Nov 15;935:175321 PMID: 36228744

Yoshitaka Sato, .et al. , Cell Commun Signal, 2022, Jun 21;20(1):95 PMID: 35729616

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

Shin-Ichi Makino, .et al. , J Am Soc Nephrol, 2021, Mar;32(3):597-613 PMID: 33510039

Yusuke Yamashita, .et al. , Int J Mol Sci, 2020, Sep; 21(17): 6314 PMID: 32878237

Nandini Verma, .et al. , Sci Adv, 2020, 6 : eaba8968

A Hayano, .et al. , Int J Clin Oncol, 2019, 1-10 PMID: 30993483

Hiroshi Fukamachi, .et al. , J Exp Clin Cancer Res, 2019, 38:127 PMID: 30866995

Y Sato, .et al. , J Virol, 2019, Jan 30. pii: JVI.01707-18 PMID: 30700607

Takashi Azuma, .et al. , SEP PURIF TECHNOL, 2019, Apr; 212: 483-489

Wenhan Deng, .et al. , Transl Oncol, 2018, Oct; 11(5): 1147-1154 PMID: 30055346

Hirosumi Tamura, .et al. , Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

Hokyung K. Chung, .et al. , Nat Chem Biol, 2015, Sep; 11(9): 713-720 PMID: 26214256

S Raz, .et al. , Cell Death Dis., 2014, 5(2): e1067 PMID: 24556682

生物活性

Discription

Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10160
分子式	C19H25BN4O4
分子量	384.2
CAS号	179324-69-7
SMILES	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
其他名称	MG-341, PS-341
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	66 mg/mL (171.77 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.03 mL	130.14 mL	260.28 mL
0.5 mM	5.21 mL	26.03 mL	52.06 mL
1 mM	2.6 mL	13.01 mL	26.03 mL
5 mM	0.52 mL	2.6 mL	5.21 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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