Bortezomib (Velcade)

目录号: A10160

Proteasome inhibitor

Bortezomib (Velcade)

Bortezomib (Velcade) Chemical Structure

CAS NO. 179324-69-7

Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome

库存: 现货

规格 价格 数量
5 mg
¥ 300.00
10 mg
¥ 580.00
25 mg
¥ 980.00
100 mg
¥ 1,600.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome
Targets
20S proteasome (Cell-free assay)
0.6 nM(Ki)
In vitro (25°C) DMSO 77 mg/mL (200.39 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.03 mL 130.14 mL 260.28 mL
0.5 mM 5.21 mL 26.03 mL 52.06 mL
1 mM 2.6 mL 13.01 mL 26.03 mL
5 mM 0.52 mL 2.6 mL 5.21 mL

*The above data is based on the productmolecular weight 384.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A10160
MECHANISM OF ACTION Inhibitor
M. Wt 384.2
Formula C19H25BN4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 179324-69-7
Synonyms MG-341, PS-341
SMILES B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O

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