Bosentan Hydrate

Name: Bosentan Hydrate
SKU: A14944
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A14944

ET-A and ET-B 拮抗剂

Bosentan 是一种内皮素（ET）受体拮抗剂，针对 ET-A 和 ET-B 的 Ki 分别为 4.7 nM 和 95 nM。

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Grouped product items
规格	价格	库存
25mg	¥210.00	现货
50mg	¥350.00	现货
100mg	¥630.00	现货
200mg	¥1,120.00	现货
500mg	¥2,065.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

产品信息

目录号	A14944
分子式	C27H29N5O6S.H2O
分子量	569.63
CAS号	157212-55-0
SMILES	CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC.O
其他名称	Ro 47-0203
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	92 mg/mL (161.51 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (3.51 mM)
In vivo	2% DMSO+30% PEG 300+2% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.56 mL	87.78 mL	175.55 mL
0.5 mM	3.51 mL	17.56 mL	35.11 mL
1 mM	1.76 mL	8.78 mL	17.56 mL
5 mM	0.35 mL	1.76 mL	3.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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