Bosentan

目录号: A11091

ETAR/ETBR 抑制剂

Bosentan

Bosentan Chemical Structure

CAS NO. 147536-97-8

Bosentan是内皮素-1(ET-A)和内皮素B(ET-B)受体的竞争性拮抗剂。

库存: 现货

规格 价格 数量
25 mg
¥ 400.00
50 mg
¥ 700.00
100 mg
¥ 1,200.00
200 mg
¥ 2,000.00
10mM * 1mL in DMSO
¥ 680.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Bosentan是内皮素-1(ET-A)和内皮素B(ET-B)受体的竞争性拮抗剂。
靶点信息
ET-A ET-B
4.7 nM(Ki)95 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.65 mL 181.29 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.06 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11091
作用机制 Inhibitor (抑制剂)
M. Wt 551.6
Formula C27H29N5O6S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 147536-97-8
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

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