Bosentan

目录号: A11091

ETAR/ETBR inhibitor

Bosentan

Bosentan Chemical Structure

CAS NO. 147536-97-8

Bosentan is a competitive antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.

库存: 现货

规格 价格 数量
25 mg
¥ 400.00
50 mg
¥ 700.00
100 mg
¥ 1,200.00
200 mg
¥ 2,000.00
10mM * 1mL in DMSO
¥ 680.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Bosentan is a competitive antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.
Targets
ET-A ET-B
4.7 nM(Ki)95 nM(Ki)
In vitro DMSO 100 mg/mL (181.28 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (5.43 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.65 mL 181.29 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.06 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11091
MECHANISM OF ACTION Inhibitor
M. Wt 551.6
Formula C27H29N5O6S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 147536-97-8
Synonyms N/A
SMILES CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=NC(=N2)C3=NC=CC=N3)OCCO)OC4=CC=CC=C4OC

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