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Bosutinib (SKI-606)


Src 抑制剂

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产品目录号: A10161


产品名 目录号 价格 数量
Bosutinib 10mg A10161-10
¥ 550.00
Bosutinib 50mg A10161-50
¥ 2,200.00
Bosutinib 100mg A10161-100
¥ 3,800.00
Bosutinib 200mg A10161-200
¥ 6,600.00
Bosutinib (SKI-606) 10mM * 1mL in DMSO A10161-10mM-D
¥ 880.00



Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.

Bosutinib (SKI-606)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Bosutinib (SKI-606) 发表的文献 (1)
  • Li Li, .et al. Evidence for activated Lck protein tyrosine kinase as the driver of proliferation in acute myeloid leukemia cell, CTV-1, Leukemia Res, 2019, 78:12-20 PMID: 30660961

Chemical Information

目录号 A10161
Mechanism of action Inhibitor
分子量 530.4
化学分子式 C26H29Cl2N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 380843-75-4
Synonyms SKI-606, SKI606
化学名称 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile


Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.
Abl (Cell-free assay) Src (Cell-free assay)
1 nM1.2 nM


Solubility (25°C)* In vitro DMSO 100 mg/mL (188.51 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (3.77 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.85 mL 94.27 mL 188.54mL
0.5 mM 3.77 mL 18.85 mL 37.71 mL
1 mM 1.89 mL 9.43 mL 18.85 mL
5 mM 0.38 mL 1.89 mL 3.77 mL

*The above data is based on the productmolecular weight 530.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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