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Bozitinib

Bozitinib

Name: Bozitinib
SKU: A18554

目录号: A18554

c-MET kinase inhibitor

Bozitinib Chemical Structure

CAS NO. 1440964-89-5

Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.

库存：现货

规格	价格	数量
5 mg	￥ 3,500.00
10 mg	￥ 6,500.00
50 mg	￥ 20,000.00

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产品详情

生物活性

溶解度 *

In vitro	DMSO	79 mg/mL (186.15 mM)
	Water	Insoluble
	Ethanol	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.56 mL	117.82 mL	235.64 mL
0.5 mM	4.71 mL	23.56 mL	47.13 mL
1 mM	2.36 mL	11.78 mL	23.56 mL
5 mM	0.47 mL	2.36 mL	4.71 mL

*The above data is based on the productmolecular weight 424.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18554
作用机制	Inhibitor (抑制剂)
M. Wt	424.38
Formula	C20H15F3N8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1440964-89-5
Synonyms	PLB-1001, PLB1001, PLB 1001
SMILES	CN1N=C2C=C(F)C(C(C3=NN=C4C=CC(C5=CN(C6CC6)N=C5)=NN43)(F)F)=CC2=C1