BPK-29
目录号: A18639
BPK-29 是一种特定的配体,通过共价修饰 C274,破坏了非典型孤儿核受体 NR0B1-蛋白(如 RBM45 和 SNW1)之间的相互作用。BPK-29 抑制了 KEAP1-突变癌细胞的锚定独立生长。
Discription | BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein (such RBM45 and SNW1) interactions by covalently modifying C274. BPK-29 impairs the anchorage-independent growth of KEAP1-mutant cancer cells. |
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目录号 | A18639 |
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分子式 | C26H32ClN3O3 |
分子量 | 470 |
CAS号 | 2143467-62-1 |
SMILES | O=C(N(C1CCN(C(C2=CC=C(N3CCOCC3)C=C2)=O)CCC1)CC4=CC=CC=C4)CCl |
其他名称 | BPK29, BPK 29 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2