BPN-15606
目录号: A18681
γ-secretase modulator
BPN-15606 是一种高效的口服活性 γ-分泌酶调节剂(GSM),通过降低SHSY5Y神经母细胞瘤细胞产生的Aβ42和Aβ40,其IC50值分别为7纳摩尔和17纳摩尔。
Discription | BPN-15606 is a highly potent, orally active γ-secretase modulator (GSM), attenuates the production of Aβ42 and Aβ40 by SHSY5Y neuroblastoma cells with IC50 values of 7 nM and 17nM, respectively. |
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目录号 | A18681 |
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分子式 | C23H23FN6O |
分子量 | 418.47 |
CAS号 | 1914989-49-3 |
SMILES | CC1=CC(C2=NC(OC)=C(N3C=C(C)N=C3)C=C2)=NN=C1N[C@H](C4=CC=C(F)C=C4)C |
其他名称 | BPN15606, BPN 15606 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2