BPN14770
目录号: A18663
PDE4D 抑制剂
BPN14770 是一种选择性磷酸二酯酶4D(PDE4D)异构抑制剂,其半抑制浓度(IC50)分别为7.8 nM和7.4 nM,针对PDE4D7和PDE4D3。
Discription | BPN14770 is a selective phosphodiesterase 4D (PDE4D) allosteric inhibitor with IC50s of 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3, respectively. | |||||
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Targets |
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Cell Research |
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目录号 | A18663 |
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分子式 | C21H15ClF3NO2 |
分子量 | 405.8 |
CAS号 | 1606974-33-7 |
SMILES | O=C(O)CC1=CC=C(CC2=CC(C3=CC=CC(Cl)=C3)=NC(C(F)(F)F)=C2)C=C1 |
其他名称 | BPN 14770, BPN-14770 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 71 mg/mL (174.96 mM) | |
Water | <1 mg/mL | ||
Ethanol | 71 mg/mL (174.96 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.64 mL | 123.21 mL | 246.43 mL |
0.5 mM | 4.93 mL | 24.64 mL | 49.29 mL |
1 mM | 2.46 mL | 12.32 mL | 24.64 mL |
5 mM | 0.49 mL | 2.46 mL | 4.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2