BQ-123
目录号: A15912
ETA receptor 拮抗剂
BQ-123 是一种选择性的内皮素 A 受体(ETA)拮抗剂,其 IC50 为 7.3 nM。处于第二阶段临床试验。
Discription | BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2. | |||||
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Targets |
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Cell Research |
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目录号 | A15912 |
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分子式 | C31H42N6O7 |
分子量 | 610.7 |
CAS号 | 136553-81-6 |
SMILES | O=C(O)C[C@H]1NC([C@@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC(C)C)NC([C@@H](C(C)C)NC([C@@](CCC4)([H])N4C1=O)=O)=O)=O)=O |
其他名称 | BQ123, BQ 123 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 87 mg/mL (142.45 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 13 mg/mL (21.29 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 16.37 mL | 81.87 mL | 163.75 mL |
0.5 mM | 3.27 mL | 16.37 mL | 32.75 mL |
1 mM | 1.64 mL | 8.19 mL | 16.37 mL |
5 mM | 0.33 mL | 1.64 mL | 3.27 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2