BQR695
目录号: A16938
PI4K 抑制剂
BQR-695,亦称为 NVP-BQR695,是一种 PI4KIIIβ 抑制剂,其对人类 PI4KIIIβ 和 疟原虫变种 PI4KIIIβ 的 IC50 分别为 80 nM 和 3.5 nM。
| Discription | BQR-695, also known as NVP-BQR695, is a PI4KIIIβ inhibitor with IC50s of 80 and 3.5 nM for human PI4KIIIβ and Plasmodium variant of PI4KIIIβ, respectively. | ||
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| Targets |
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| 目录号 | A16938 |
|---|---|
| 分子式 | C19H20N4O3 |
| 分子量 | 352.39 |
| CAS号 | 1513879-21-4 |
| SMILES | O=C(NC)CNC1=NC2=CC(C3=CC=C(OC)C(OC)=C3)=CC=C2N=C1 |
| 其他名称 | NVP-BQR695, NVP-BQR-695, NVP-BQR 695, BQR-695, BQR 695 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 63 mg/mL (178.78 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (8.51 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.38 mL | 141.89 mL | 283.78 mL |
| 0.5 mM | 5.68 mL | 28.38 mL | 56.76 mL |
| 1 mM | 2.84 mL | 14.19 mL | 28.38 mL |
| 5 mM | 0.57 mL | 2.84 mL | 5.68 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2