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Branebrutinib

Branebrutinib

Name: Branebrutinib
SKU: A20043

目录号: A20043

BTK inhibitor

Branebrutinib Chemical Structure

CAS NO. 1912445-55-6

Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Bruton??s tyrosine kinase (BTK), with an IC50 of 0.1 nM.

库存：现货

规格	价格	数量
5 mg	￥ 1,710.00
10 mg	￥ 2,950.00
50 mg	￥ 8,740.00
100 mg	￥ 17,480.00

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生物活性

Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Bruton??s tyrosine kinase (BTK), with an IC50 of 0.1 nM.

溶解度 *

In vitro	DMSO	73 mg/mL (197.07 mM)
	Water	Insoluble
	Ethanol	38 mg/mL (102.58 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27 mL	134.98 mL	269.96 mL
0.5 mM	5.4 mL	27 mL	53.99 mL
1 mM	2.7 mL	13.5 mL	27 mL
5 mM	0.54 mL	2.7 mL	5.4 mL

*The above data is based on the productmolecular weight 370.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20043
M. Wt	370.42
Formula	C20H23FN4O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1912445-55-6
Synonyms	BMS-986195, BMS986195, BMS 986195
SMILES	O=C(C1=CC(F)=C(N2C[C@@H](NC(C#CC)=O)CCC2)C3=C1NC(C)=C3C)N