产品详情
BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.36 mL | 91.82 mL | 183.64 mL |
0.5 mM | 3.67 mL | 18.36 mL | 36.73 mL |
1 mM | 1.84 mL | 9.18 mL | 18.36 mL |
5 mM | 0.37 mL | 1.84 mL | 3.67 mL |
*The above data is based on the productmolecular weight 544.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20464 |
---|---|
M. Wt | 544.54 |
Formula | C26H33N4O7P |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1622262-55-8 |
SMILES | O=C(N[C@@H](COP(O)(O)=O)C(NCC(NCCCCC1=CC=CC=C1)=O)=O)CCC2=CNC3=C2C=CC=C3 |
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