BRD4 Inhibitor-10
目录号: A18679
BRD4-BD1 抑制剂
BRD4 Inhibitor-10 是一种强效的 BRD4-BD1 抑制剂,源自专利 WO2015022332A1,化合物 II-25,具有 8 nM 的 IC50。
Discription | BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM. | ||
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Targets |
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目录号 | A18679 |
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分子式 | C25H27N5O2 |
分子量 | 429.51 |
CAS号 | 1660117-38-3 |
SMILES | CN1C(C(C)=CC(C2=NC3=CN=C(C=C3N2[C@H](C4=CC=CC=C4)C)C5CCOCC5)=N1)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 83 mg/mL (193.24 mM) | |
Water | Insoluble | ||
Ethanol | 83 mg/mL (193.24 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 23.28 mL | 116.41 mL | 232.82 mL |
0.5 mM | 4.66 mL | 23.28 mL | 46.56 mL |
1 mM | 2.33 mL | 11.64 mL | 23.28 mL |
5 mM | 0.47 mL | 2.33 mL | 4.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2