Brequinar
目录号: A12442
Dihydroorotate Dehydrogenase 抑制剂
Brequinar 是一种二氢乳清酸脱氢酶抑制剂，这种酶对于新生嘧啶生物合成是必需的。
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生物活性
| Discription | Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. | |||||
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| Cell Research |
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产品信息
| 目录号 | A12442 |
|---|---|
| 分子式 | C22H13F2NO2 |
| 分子量 | 375.37 |
| CAS号 | 96187-53-0 |
| SMILES | CC1=C(N=C2C=CC(=CC2=C1C(=O)O)F)C3=CC=C(C=C3)C4=CC=CC=C4F |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 36 mg/mL (95.9 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.64 mL | 133.2 mL | 266.4 mL |
| 0.5 mM | 5.33 mL | 26.64 mL | 53.28 mL |
| 1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
| 5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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