Brigatinib (AP26113)

目录号: A13450

ALK Inhibitor

Brigatinib (AP26113) Chemical Structure

CAS NO. 1197953-54-0

Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits ROS1, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.

库存: 现货

规格 价格 数量
5 mg
¥ 450.00
10 mg
¥ 650.00
25 mg
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Brigatinib (AP26113) is a potent and selective ALK (IC50, 0.6 nM) and ROS1 (IC50, 0.9 nM) inhibitor. It also inhibits ROS1, FLT3, and mutant variants of FLT3 (D835Y) and EGFR with lower potentcy.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.12 mL 85.6 mL 171.21 mL
0.5 mM 3.42 mL 17.12 mL 34.24 mL
1 mM 1.71 mL 8.56 mL 17.12 mL
5 mM 0.34 mL 1.71 mL 3.42 mL

*The above data is based on the productmolecular weight 584.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13450
MECHANISM OF ACTION Inhibitor
M. Wt 584.09
Formula C29H39ClN7O2P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1197953-54-0
Synonyms AP-26113, AP 26113, AP26113
SMILES CN1CCN(CC1)C2CCN(CC2)C3=CC(=C(C=C3)NC4=NC=C(C(=N4)NC5=CC=CC=C5P(=O)(C)C)Cl)OC

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